Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50047095
TargetKappa-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM224024(Dynorphin A (1-13) | YGGFLRRXRPKLK | BDBM50241435)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human recombinant KOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148259(CHEMBL3765406)
Affinity DataEC50:  813nMAssay Description:Agonist activity at human recombinant KOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM224024(Dynorphin A (1-13) | YGGFLRRXRPKLK | BDBM50241435)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human recombinant DOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human recombinant DOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataEC50:  372nMAssay Description:Agonist activity at human recombinant DOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM224024(Dynorphin A (1-13) | YGGFLRRXRPKLK | BDBM50241435)
Affinity DataEC50:  214nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50166066(CHEMBL362991 | Tyr-Pro-Phe-Pro-NH2 | [D-Pro4]morph...)
Affinity DataEC50:  741nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148259(CHEMBL3765406)
Affinity DataEC50:  4.70nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148258(CHEMBL3764033)
Affinity DataEC50:  398nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148257(CHEMBL3764219)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148259(CHEMBL3765406)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148257(CHEMBL3764219)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50166066(CHEMBL362991 | Tyr-Pro-Phe-Pro-NH2 | [D-Pro4]morph...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148258(CHEMBL3764033)
Affinity DataKi:  106nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148259(CHEMBL3765406)
Affinity DataKi:  386nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148258(CHEMBL3764033)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148257(CHEMBL3764219)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148256(CHEMBL3765790)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148259(CHEMBL3765406)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148258(CHEMBL3764033)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148257(CHEMBL3764219)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148256(CHEMBL3765790)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50148256(CHEMBL3765790)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50166066(CHEMBL362991 | Tyr-Pro-Phe-Pro-NH2 | [D-Pro4]morph...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50166066(CHEMBL362991 | Tyr-Pro-Phe-Pro-NH2 | [D-Pro4]morph...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenate by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed