Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50047187
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152733(CHEMBL3781564)
Affinity DataIC50: 300nMAssay Description:Inhibition of human AChE assessed as hydrolytic activity using acetylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152733(CHEMBL3781564)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human BuChE assessed as hydrolytic activity using butyrylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152738(CHEMBL3781022)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation measured after 24 hrs by Thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152737(CHEMBL3781419)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation measured after 24 hrs by Thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152739(CHEMBL3781026)
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation measured after 24 hrs by Thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152735(CHEMBL3780448)
Affinity DataIC50: 8.08E+4nMAssay Description:Inhibition of human AChE assessed as hydrolytic activity using acetylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152736(CHEMBL3780131)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of human AChE assessed as hydrolytic activity using acetylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152735(CHEMBL3780448)
Affinity DataIC50: 1.64E+5nMAssay Description:Inhibition of human BuChE assessed as hydrolytic activity using butyrylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152736(CHEMBL3780131)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human BuChE assessed as hydrolytic activity using butyrylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed