Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 7319
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 20nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris HCl buffer (25 mL, 60 mm, pH 8.1) cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189342(RDS1759)
Affinity DataIC50: 7.50E+3nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189337(STOCK5S-18255 (2))
Affinity DataIC50: 2.50E+4nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189341(STOCK4S-60534 (6))
Affinity DataIC50: 2.85E+4nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris HCl buffer (25 mL, 60 mm, pH 8.1) cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189341(STOCK4S-60534 (6))
Affinity DataIC50: 3.30E+4nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189337(STOCK5S-18255 (2))
Affinity DataIC50: 6.90E+4nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris HCl buffer (25 mL, 60 mm, pH 8.1) cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM60932(STOCK4S-37006 (4))
Affinity DataIC50: 9.70E+4nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189336(MAS0 (1))
Affinity DataIC50: 1.00E+5nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189336(MAS0 (1))
Affinity DataIC50: 1.00E+5nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris HCl buffer (25 mL, 60 mm, pH 8.1) cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM60932(STOCK4S-37006 (4))
Affinity DataIC50: 1.00E+5nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris HCl buffer (25 mL, 60 mm, pH 8.1) cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189340(STOCK5S-55040 (5))
Affinity DataIC50: 1.00E+5nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189340(STOCK5S-55040 (5))
Affinity DataIC50: 1.00E+5nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris HCl buffer (25 mL, 60 mm, pH 8.1) cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189338(STOCK2S-18057 (3))
Affinity DataIC50: 1.00E+5nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189338(STOCK2S-18057 (3))
Affinity DataIC50: 1.00E+5nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris HCl buffer (25 mL, 60 mm, pH 8.1) cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed