Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50047261
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50157638(CHEMBL3787137)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50157638(CHEMBL3787137)
Affinity DataIC50: 30nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50157639(CHEMBL3786413)
Affinity DataIC50: 300nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50156385(CHEMBL2163553)
Affinity DataIC50: 500nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50157637(CHEMBL3785463)
Affinity DataIC50: 700nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50156442(CHEMBL3786170)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50156388(CHEMBL3786155)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50156443(CHEMBL3785863)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50156387(CHEMBL3785302)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50156386(CHEMBL3785354)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed