Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50047467
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50265275(4-(4-iodophenoxy)-2-(2H-tetrazol-5-yl)thieno[2,3-c...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169081(CHEMBL3806220)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169082(CHEMBL3805960)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50265311(4-(4-chlorophenoxy)-2-(2H-tetrazol-5-yl)thieno[2,3...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169062(CHEMBL3805194)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50265309(2-(2H-tetrazol-5-yl)-4-(p-tolyloxy)thieno[2,3-c]py...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169080(CHEMBL3806173)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169078(CHEMBL3804919)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50264866(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169079(CHEMBL3805857)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105215(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169071(CHEMBL3806024)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169083(CHEMBL3805667)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105170(4-p-Tolyloxy-thieno[2,3-c]pyridine-2-carboxylic ac...)
Affinity DataIC50: 6nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105181(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169064(CHEMBL3806134)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105159(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50265277(4-phenoxy-2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169067(CHEMBL3805684)
Affinity DataIC50: 11nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169070(CHEMBL3806182)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105153(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169068(CHEMBL3806291)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169069(CHEMBL3806265)
Affinity DataIC50: 21nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169076(CHEMBL3806114)
Affinity DataIC50: 24nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105218(4-(4-Methoxy-phenoxy)-thieno[2,3-c]pyridine-2-carb...)
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105206(4-(4-Acetylamino-phenoxy)-thieno[2,3-c]pyridine-2-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169073(CHEMBL3805204)
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169074(CHEMBL3806037)
Affinity DataIC50: 32nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169072(CHEMBL3806125)
Affinity DataIC50: 59nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169077(CHEMBL3805018)
Affinity DataIC50: 62nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105152(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: 75nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169075(CHEMBL3805581)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50169062(CHEMBL3805194)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full length human recombinant His-tagged CDK9/Cyclin T expressed in baculovirus expression system using Cdk7/9tide as substrate by adap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50105181(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of full length human recombinant His-tagged CDK9/Cyclin T expressed in baculovirus expression system using Cdk7/9tide as substrate by adap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed