Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50047480
TargetMycocyclosin synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM31774(cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...)
Affinity DataKd:  73nMAssay Description:Binding affinity to Mycobacterium tuberculosis H37Rv wild type CYP121 by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMycocyclosin synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM31773(ECONAZOLE | cid_68589 | Pevaryl | Gyno-pevaryl | E...)
Affinity DataKd:  73nMAssay Description:Binding affinity to Mycobacterium tuberculosis H37Rv wild type CYP121 by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMycocyclosin synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM31772(Brentan | 1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dich...)
Affinity DataKd:  73nMAssay Description:Binding affinity to Mycobacterium tuberculosis H37Rv wild type CYP121 by titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169700(CHEMBL3806115)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169698(CHEMBL3806191)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169700(CHEMBL3806115)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169702(CHEMBL3805279)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169698(CHEMBL3806191)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using mephenytoin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169700(CHEMBL3806115)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using mephenytoin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169702(CHEMBL3805279)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using mephenytoin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169698(CHEMBL3806191)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169700(CHEMBL3806115)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169702(CHEMBL3805279)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169698(CHEMBL3806191)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169702(CHEMBL3805279)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed