Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50047526
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 250nMAssay Description:Inhibition of Nav1.5 (unknown origin) assessed as inhibition of late sodium current by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 333nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 400nMAssay Description:Inhibition of 1 Hz stimulated Nav1.2 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 1 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 400nMAssay Description:Inhibition of 10 Hz stimulated Nav1.1 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin) assessed as inhibition of late sodium current by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173302(CHEMBL3809055)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173241(CHEMBL3808641)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173143(CHEMBL3810355)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173142(CHEMBL3810147)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 3 Hz stimulated Nav1.5 (unknown origin) assessed as inhibition of peak sodium current by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173242(CHEMBL3808635)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173239(CHEMBL3810138)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173240(CHEMBL3809561)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of 1 Hz stimulated Nav1.2 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 1 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of 10 Hz stimulated Nav1.1 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of 10 Hz stimulated Nav1.2 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of 10 Hz stimulated Nav1.2 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173304(CHEMBL3808881)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173303(CHEMBL3809560)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 1 Hz stimulated Nav1.5 (unknown origin) assessed as inhibition of peak sodium current by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 1 Hz stimulated Nav1.5 (unknown origin) assessed as inhibition of peak sodium current by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 3 Hz stimulated Nav1.5 (unknown origin) assessed as inhibition of peak sodium current by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 1 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 1 Hz stimulated Nav1.1 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 1 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173135(CHEMBL3809641)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 1 Hz stimulated Nav1.1 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173136(CHEMBL2147142)
Affinity DataIC50: 1.34E+5nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173141(CHEMBL2147143)
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173139(CHEMBL3809744)
Affinity DataIC50: 5.41E+5nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173137(CHEMBL3809097)
Affinity DataIC50: 7.40E+5nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173138(CHEMBL3810356)
Affinity DataIC50: 9.81E+5nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173140(CHEMBL3810384)
Affinity DataIC50: 1.90E+6nMAssay Description:Inhibition of 0.1 Hz stimulated human Nav1.5alpha expressed in HEK293 cells assessed as inhibition of late sodium current with 3 compound additions f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMed