Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50001758
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017865(CHEMBL265218 | 2,5-Bis-(3,4-dihydroxy-5-nitro-benz...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017845(CHEMBL168600 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(CHEMBL169926 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017846(CHEMBL168276 | 3,5-DINITROCATECHOL | 3,5-Dinitro-b...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017852(CHEMBL167054 | 4-(3,4-Dihydroxy-5-nitro-phenyl)-3-...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017844(CHEMBL169033 | 1-(3,4-Dihydroxy-5-nitro-phenyl)-et...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017848(CHEMBL167055 | 3-(3,4-Dihydroxy-5-nitro-benzyliden...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017861(CHEMBL168389 | 2-Cyano-3-(3,4-dihydroxy-5-nitro-ph...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017866(CHEMBL350927 | N-Adamantan-1-yl-3,4-dihydroxy-5-ni...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017871(AG-1288 | 2-(3,4-dihydroxy-5-nitrobenzylidene)malo...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50004043(3,4-Dihydroxy-5-nitro-benzaldehyde | CHEMBL1244 | ...)
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017867(CHEMBL355017 | 5-Chloro-3-nitro-benzene-1,2-diol)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017856(CHEMBL169891 | 3,4-Dihydroxy-5-nitro-benzonitrile)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017870(CHEMBL353012 | 2-Cyano-3-(3,4-dihydroxy-5-nitro-ph...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017863(CHEMBL167172 | N-Adamantan-1-yl-3-cyano-4,5-dihydr...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017853(CHEMBL353188 | 5-(3,4-Dihydroxy-5-nitro-phenyl)-pe...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017860(CHEMBL355736 | 4,5-Dihydroxy-benzene-1,3-dicarbald...)
Affinity DataIC50: 160nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017862(CHEMBL169465 | 5-Formyl-2,3-dihydroxy-benzonitrile)
Affinity DataIC50: 160nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017869(CHEMBL355402 | 5-Hydroxymethyl-3-nitro-benzene-1,2...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017868(CHEMBL168451 | N-Adamantan-1-yl-3-chloro-4,5-dihyd...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017858(CHEMBL170549 | 3,4-Dihydroxy-5-nitro-benzoic acid)
Affinity DataIC50: 620nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017859(CHEMBL352270 | N-Adamantan-1-yl-4,5-dihydroxy-2-ni...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017851(CHEMBL354517 | 3-(3,4-Dihydroxy-5-trifluoromethyl-...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017847(CHEMBL166908 | 3,4-Dihydroxy-5-trifluoromethyl-ben...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017849(CHEMBL169679 | N-Adamantan-1-yl-2-chloro-4,5-dihyd...)
Affinity DataIC50: 2.70E+3nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017850(CHEMBL353187 | 1-(3,4-Dihydroxy-phenyl)-2-methyl-p...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017855(CHEMBL168818 | 5-(3-Chloro-4,5-dihydroxy-phenyl)-p...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017854(CHEMBL169208 | N-Adamantan-1-yl-2-chloro-3,4-dihyd...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Orion

Curated by ChEMBL
LigandPNGBDBM50017864(CHEMBL353983 | 3,4-Dihydroxy-5-methanesulfonyl-ben...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine 3-monooxygenase(Bovine)
Orion

Curated by ChEMBL
LigandPNGBDBM50017845(CHEMBL168600 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity against the tyrosine hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine 3-monooxygenase(Bovine)
Orion

Curated by ChEMBL
LigandPNGBDBM50017850(CHEMBL353187 | 1-(3,4-Dihydroxy-phenyl)-2-methyl-p...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory activity against the tyrosine hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine 3-monooxygenase(Bovine)
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(CHEMBL169926 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the tyrosine hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Mouse)
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(CHEMBL169926 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the Monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017857(CHEMBL169926 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Mouse)
Orion

Curated by ChEMBL
LigandPNGBDBM50017845(CHEMBL168600 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the Monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(CHEMBL169926 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017850(CHEMBL353187 | 1-(3,4-Dihydroxy-phenyl)-2-methyl-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the dopamine decarboxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017857(CHEMBL169926 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the dopamine decarboxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017850(CHEMBL353187 | 1-(3,4-Dihydroxy-phenyl)-2-methyl-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017845(CHEMBL168600 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the dopamine decarboxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Orion

Curated by ChEMBL
LigandPNGBDBM50017845(CHEMBL168600 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Orion

Curated by ChEMBL
LigandPNGBDBM50017850(CHEMBL353187 | 1-(3,4-Dihydroxy-phenyl)-2-methyl-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Mouse)
Orion

Curated by ChEMBL
LigandPNGBDBM50017850(CHEMBL353187 | 1-(3,4-Dihydroxy-phenyl)-2-methyl-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the Monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017845(CHEMBL168600 | 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against the Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed