Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50047591
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of full length recombinant human GST or His-tagged VEGFR2 using poly (Glu, Tyr) as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate preincubated for 60 mins followed by substrate addition measured after 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate preincubated for 60 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length recombinant human GST or His-tagged c-Met using poly (Glu, Tyr) as substrate by luciferase coupled chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177048(CHEMBL3814321)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177047(CHEMBL3814311)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM12318(6-(1H-indol-5-yloxy)-5-[(1E)-(methoxyimino)methyl]...)
Affinity DataIC50: 146nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177113(CHEMBL3815128)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177113(CHEMBL3815128)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177116(CHEMBL3814710)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177050(CHEMBL3815081)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177050(CHEMBL3815081)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177047(CHEMBL3814311)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177049(CHEMBL3813791)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177115(CHEMBL3814828)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177048(CHEMBL3814321)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177116(CHEMBL3814710)
Affinity DataIC50: 420nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177049(CHEMBL3813791)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177112(CHEMBL3814773)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177115(CHEMBL3814828)
Affinity DataIC50: 920nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177112(CHEMBL3814773)
Affinity DataIC50: 980nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177046(CHEMBL3813717)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50177046(CHEMBL3813717)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed