Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50047534
TargetAcetylcholinesterase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 7nMAssay Description:Inhibition of AchE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50029946(CHEMBL355160 | CHEMBL540607 | 2-(1-Cyclohexylmethy...)
Affinity DataIC50: 9nMAssay Description:Inhibition of AchE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM25731(CHEMBL1458 | 1,3-dicyclohexylurea | US8815951, 1,3...)
Affinity DataIC50: 25nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50167056(CHEMBL365939 | US8815951, 21 | 1-Cyclohexyl-3-phen...)
Affinity DataIC50: 760nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetAminopeptidase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50010157(CHEMBL3251698)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of aminopeptidase B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetAminopeptidase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of aminopeptidase B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM32658(m-chlorobenzylamide, 7)
Affinity DataKi:  100nMAssay Description:Inhibition of human thrombin using pefachrom tPa as substrate after 3 mins by photometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM32653(m-chlorobenzylamide, 2)
Affinity DataKi:  180nMAssay Description:Inhibition of human thrombin using pefachrom tPa as substrate after 3 mins by photometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed