Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50047698
LigandPNGBDBM50184765(CHEMBL3823499)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat RIPK2 preincubated for 10 mins followed by addition of fluorescent-labeled 2-Methyl-5-(2-propen-l-yloxy)aniline measured after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50: 3nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50: 3.20nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50184765(CHEMBL3823499)
Affinity DataIC50: 5nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184479(CHEMBL3822791)
Affinity DataIC50: 6.30nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184727(CHEMBL3822938)
Affinity DataIC50: 8nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM25195(4-methyl-3-{[6-(pyridin-3-yl)quinolin-4-yl]amino}p...)
Affinity DataIC50: 10nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184764(CHEMBL3822577)
Affinity DataIC50: 10nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184765(CHEMBL3823499)
Affinity DataIC50: 16nMAssay Description:Inhibition of RIPK3 (unknown origin) preincubated for 10 mins followed by addition of fluorescent-labeled 2-Methyl-5-(2-propen-l-yloxy)aniline measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184765(CHEMBL3823499)
Affinity DataIC50: 18nMAssay Description:Inhibition of RIP2K in MDP-stimulated HEK-293 cells over-expressing NOD2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184725(CHEMBL3824056)
Affinity DataIC50: 20nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of RIP2K in MDP-stimulated HEK-293 cells over-expressing NOD2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50184548(CHEMBL3822754)
Affinity DataIC50: 50nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184478(CHEMBL3823809)
Affinity DataIC50: 50nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184727(CHEMBL3822938)
Affinity DataIC50: 100nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50: 186nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184726(CHEMBL3823527)
Affinity DataIC50: 250nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50: 250nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50: 250nMAssay Description:Inhibition of RIP2K in MDP-stimulated HEK-293 cells over-expressing NOD2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50: 251nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184477(CHEMBL3822979)
Affinity DataIC50: 320nMAssay Description:Inhibition of RIP2K in MDP-stimulated HEK-293 cells over-expressing NOD2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25195(4-methyl-3-{[6-(pyridin-3-yl)quinolin-4-yl]amino}p...)
Affinity DataIC50: 460nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50: 500nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184620(CHEMBL3822573)
Affinity DataIC50: 630nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184477(CHEMBL3822979)
Affinity DataIC50: 790nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184477(CHEMBL3822979)
Affinity DataIC50: 794nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184727(CHEMBL3822938)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184477(CHEMBL3822979)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of RIP2K in Pam2CSK4-stimulated HEK-293 cells over-expressing TLR2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184479(CHEMBL3822791)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184726(CHEMBL3823527)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25195(4-methyl-3-{[6-(pyridin-3-yl)quinolin-4-yl]amino}p...)
Affinity DataIC50: 3.74E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184478(CHEMBL3823809)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184764(CHEMBL3822577)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184765(CHEMBL3823499)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184725(CHEMBL3824056)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184478(CHEMBL3823809)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184620(CHEMBL3822573)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184548(CHEMBL3822754)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of VEGFR2(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184548(CHEMBL3822754)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184479(CHEMBL3822791)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184764(CHEMBL3822577)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184726(CHEMBL3823527)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184725(CHEMBL3824056)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184620(CHEMBL3822573)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184765(CHEMBL3823499)
Affinity DataIC50: 5.12E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of RIP2K in Pam2CSK4-stimulated HEK-293 cells over-expressing TLR2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50184765(CHEMBL3823499)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RIP2K in Pam2CSK4-stimulated HEK-293 cells over-expressing TLR2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RIP2K in Pam2CSK4-stimulated HEK-293 cells over-expressing TLR2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)