Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 7504
TargetHistone deacetylase 8(Human)
Shandong University

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.10E+3nMAssay Description:Briefly, the HDAC8 enzyme was diluted 20 times. Then, 10 μL of HDAC8 solution was mixed with compounds at various concentrations (50 μL). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAminopeptidase N(Pig)
Shandong University

LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 2.50E+3nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

LigandPNGBDBM198191(N1-hydroxy-N4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Affinity DataIC50: 4.30E+3nMAssay Description:Briefly, the HDAC8 enzyme was diluted 20 times. Then, 10 μL of HDAC8 solution was mixed with compounds at various concentrations (50 μL). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 1.00E+5nMAssay Description:Briefly, the HDAC8 enzyme was diluted 20 times. Then, 10 μL of HDAC8 solution was mixed with compounds at various concentrations (50 μL). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Shandong University

LigandPNGBDBM198191(N1-hydroxy-N4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Affinity DataIC50: 1.00E+5nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Shandong University

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+5nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Shandong University

LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 1.00E+5nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed