Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50047667
TargetProtein polybromo-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182280(CHEMBL3819245)
Affinity DataKd:  28nMAssay Description:Binding affinity to human PB1 isoform 5 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50182279(CHEMBL3818070)
Affinity DataKd:  37nMAssay Description:Binding affinity to human SMARCA2 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription activator BRG1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182280(CHEMBL3819245)
Affinity DataKd:  49nMAssay Description:Binding affinity to human SMARCA4 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50158688(CHEMBL3752911)
Affinity DataKd: <100nMAssay Description:Binding affinity to human PB1 isoform 5 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMed
TargetTranscription activator BRG1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50158688(CHEMBL3752911)
Affinity DataKd: <100nMAssay Description:Binding affinity to human SMARCA4 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein polybromo-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182280(CHEMBL3819245)
Affinity DataKd:  152nMAssay Description:Binding affinity to human PB1 isoform 2 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration CalorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMed