Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50047761
TargetSteryl-sulfatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50188235(CHEMBL3827021)
Affinity DataIC50: 1nMAssay Description:Inhibition of placental sulphatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human placental microsomal aromatase using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50180683(CHEMBL3818720)
Affinity DataIC50: 80nMAssay Description:Inhibition of aromatase in human MCF7 cells using [1beta-3H]androstenedione as substrate measured after 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50188234(CHEMBL269221)
Affinity DataIC50: 380nMAssay Description:Inhibition of sulphatase in human MCF7 cells assessed as inhibition of E1-STS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM23419(CHEMBL9352 | (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of aromatase (unknown origin) preincubated for 10 mins in presence of NADPH generating system followed by addition of dibenzylfluorescein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM23419(CHEMBL9352 | (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of aromatase in human MCF7 cells using [1beta-3H]androstenedione as substrate measured after 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM92556(Neoflavonoid, 8)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of aromatase (unknown origin) preincubated for 10 mins in presence of NADPH generating system followed by addition of dibenzylfluorescein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM92557(Neoflavonoid, 9)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of aromatase (unknown origin) preincubated for 10 mins in presence of NADPH generating system followed by addition of dibenzylfluorescein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed