Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50047602
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM109086(US8604016, 670 | US9938267, Cmpd ID 670 | US107935...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178230(CHEMBL3814265 | US11191732, Example 5)
Affinity DataIC50: 70nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108730(US8604016, 375 | US9938267, Cmpd ID 309)
Affinity DataIC50: 70nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108731(US8604016, 310 | US9938267, Cmpd ID 310)
Affinity DataIC50: 70nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178229(CHEMBL3814401)
Affinity DataIC50: 110nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178226(CHEMBL3813967)
Affinity DataIC50: 120nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178235(CHEMBL3814231)
Affinity DataIC50: 120nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178224(CHEMBL3814214)
Affinity DataIC50: 120nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178222(CHEMBL3814899)
Affinity DataIC50: 140nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178234(CHEMBL3814007)
Affinity DataIC50: 170nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178260(CHEMBL3813769)
Affinity DataIC50: 210nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178259(CHEMBL3813734)
Affinity DataIC50: 380nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178231(CHEMBL3815103)
Affinity DataIC50: 450nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178223(CHEMBL3813810)
Affinity DataIC50: 510nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178233(CHEMBL3814398)
Affinity DataIC50: 540nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178227(CHEMBL3814427)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108464(US8604016, 21 | US9938267, Cmpd ID 21)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178225(CHEMBL3814388)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178228(CHEMBL3814255)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178236(CHEMBL3814199)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178232(CHEMBL3814303)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50178237(CHEMBL3814504)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed