Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50047769
TargetTrypsin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189306(CHEMBL3594083)
Affinity DataKi:  192nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189311(CHEMBL181480 | 4,4''-(1,2-Phenylenebis(Methylene))...)
Affinity DataKi:  221nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189307(CHEMBL3594082)
Affinity DataKi:  244nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189311(CHEMBL181480 | 4,4''-(1,2-Phenylenebis(Methylene))...)
Affinity DataKi:  279nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189310(CHEMBL365916 | 4,4''-(1,4-Phenylenebis(Methylene))...)
Affinity DataKi:  316nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189306(CHEMBL3594083)
Affinity DataKi:  317nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189310(CHEMBL365916 | 4,4''-(1,4-Phenylenebis(Methylene))...)
Affinity DataKi:  327nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189307(CHEMBL3594082)
Affinity DataKi:  391nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  397nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  492nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189307(CHEMBL3594082)
Affinity DataKi:  499nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  513nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189306(CHEMBL3594083)
Affinity DataKi:  526nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189307(CHEMBL3594082)
Affinity DataKi:  558nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  719nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189310(CHEMBL365916 | 4,4''-(1,4-Phenylenebis(Methylene))...)
Affinity DataKi:  816nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189310(CHEMBL365916 | 4,4''-(1,4-Phenylenebis(Methylene))...)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189306(CHEMBL3594083)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189306(CHEMBL3594083)
Affinity DataKi:  1.64E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTrypsin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189311(CHEMBL181480 | 4,4''-(1,2-Phenylenebis(Methylene))...)
Affinity DataKi:  2.28E+3nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189310(CHEMBL365916 | 4,4''-(1,4-Phenylenebis(Methylene))...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of bovine thrombin using BANA/BPVANA as substrate after 15 to 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189307(CHEMBL3594082)
Affinity DataKi:  3.68E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  4.39E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189311(CHEMBL181480 | 4,4''-(1,2-Phenylenebis(Methylene))...)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189310(CHEMBL365916 | 4,4''-(1,4-Phenylenebis(Methylene))...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  6.23E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189308(CHEMBL269032)
Affinity DataKi:  7.83E+3nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  1.01E+4nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189311(CHEMBL181480 | 4,4''-(1,2-Phenylenebis(Methylene))...)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  5.23E+4nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed