Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50047628
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 0.760nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180271(CHEMBL3814601)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180269(CHEMBL3814367)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180272(CHEMBL3814223)
Affinity DataIC50: 25nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180276(CHEMBL3814939)
Affinity DataIC50: 130nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180275(CHEMBL3813874)
Affinity DataIC50: 170nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180273(CHEMBL3815042)
Affinity DataIC50: 550nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180270(CHEMBL3815110)
Affinity DataIC50: 760nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180311(CHEMBL3813937)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180312(CHEMBL3814288)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180274(CHEMBL3814101)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE2A3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE3AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE4D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE5A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE6ABMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE7BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE8A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE9A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50180268(CHEMBL3814662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE11A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed