Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50009830
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50152234(N*5*-{2-[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-e...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50152234(N*5*-{2-[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-e...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50152237(2-Furan-2-yl-N*5*-[3-(4-phenyl-piperazin-1-yl)-pro...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50152237(2-Furan-2-yl-N*5*-[3-(4-phenyl-piperazin-1-yl)-pro...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50532555(CHEMBL3937413)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50532555(CHEMBL3937413)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50532554(CHEMBL3934661)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50532554(CHEMBL3934661)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-ZM241385 from wild type human adenosine receptor A2a expressed in HEK293 cell membranes after 240 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)