Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50047893
TargetProteasome subunit beta type-5(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataKi:  1.40nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-5(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195937(CHEMBL3919583)
Affinity DataKi:  420nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195935(CHEMBL3929092)
Affinity DataKi:  2.12E+3nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195934(CHEMBL3977256)
Affinity DataKi:  2.18E+3nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195936(CHEMBL3612420)
Affinity DataKi:  4.70E+3nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataKi:  5.52E+3nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-1(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195934(CHEMBL3977256)
Affinity DataKi:  8.59E+3nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195933(CHEMBL3612421)
Affinity DataKi:  1.03E+4nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195938(CHEMBL3961750)
Affinity DataKi:  1.10E+4nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataKi:  2.21E+4nMAssay Description:Competitive inhibition of trypsin-like activity of human 20S proteasome using Boc-Leu-Arg-Arg-AMC as substrate measured for 10 mins by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-1(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195936(CHEMBL3612420)
Affinity DataKi:  3.13E+4nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed