Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50047943
Affinity DataIC50: 0.100nMAssay Description:Agonist activity at human recombinant ETB receptor expressed in CHOK1 cells assessed as induction of Ca2+ mobilization by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Antagonist activity at ETB receptor in human BSMC assessed as inhibition of endothelin-1 or 3-mediated Ca2+ mobilization preincubated for 5 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Antagonist activity at ETA receptor in human SKNMC cells assessed as inhibition of endothelin-1-mediated Ca2+ mobilization by fura-2/AM dye-based spe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Agonist activity at ETA receptor in human SKNMC cells assessed as induction of Ca2+ mobilization by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Binding affinity to human ETA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Agonist activity at ETA receptor in human SKNMC cells assessed as induction of Ca2+ mobilization by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Binding affinity to human ETB receptorMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 6.93E+5nMAssay Description:Agonist activity at ETA receptor in human SKNMC cells assessed as induction of Ca2+ mobilization by fluorimetric methodMore data for this Ligand-Target Pair
