Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50009833
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532620(CHEMBL4440347)
Affinity DataIC50: 4.20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532620(CHEMBL4440347)
Affinity DataIC50: 4.20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532615(CHEMBL4549408)
Affinity DataIC50: 8.90nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532615(CHEMBL4549408)
Affinity DataIC50: 8.90nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532614(CHEMBL4566932)
Affinity DataIC50: 10nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532614(CHEMBL4566932)
Affinity DataIC50: 10nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532628(CHEMBL4461493)
Affinity DataIC50: 15nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532628(CHEMBL4461493)
Affinity DataIC50: 15nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532619(CHEMBL4568245)
Affinity DataIC50: 15nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532619(CHEMBL4568245)
Affinity DataIC50: 15nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532616(CHEMBL4532382)
Affinity DataIC50: 17nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532616(CHEMBL4532382)
Affinity DataIC50: 17nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532623(CHEMBL4530828)
Affinity DataIC50: 18nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532623(CHEMBL4530828)
Affinity DataIC50: 18nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532622(CHEMBL4581368)
Affinity DataIC50: 20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532622(CHEMBL4581368)
Affinity DataIC50: 20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532627(CHEMBL4514427)
Affinity DataIC50: 21nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532627(CHEMBL4514427)
Affinity DataIC50: 21nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 33nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 33nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532635(CHEMBL4472665)
Affinity DataIC50: 40nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532635(CHEMBL4472665)
Affinity DataIC50: 40nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532633(CHEMBL4449425)
Affinity DataIC50: 42nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532633(CHEMBL4449425)
Affinity DataIC50: 42nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532631(CHEMBL4586753)
Affinity DataIC50: 44nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532631(CHEMBL4586753)
Affinity DataIC50: 44nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532617(CHEMBL4471643)
Affinity DataIC50: 60nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532617(CHEMBL4471643)
Affinity DataIC50: 60nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532632(CHEMBL4450385)
Affinity DataIC50: 100nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532632(CHEMBL4450385)
Affinity DataIC50: 100nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532629(CHEMBL4462162)
Affinity DataIC50: 117nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532629(CHEMBL4462162)
Affinity DataIC50: 117nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532624(CHEMBL4548888)
Affinity DataIC50: 143nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532624(CHEMBL4548888)
Affinity DataIC50: 143nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532634(CHEMBL4451530)
Affinity DataIC50: 157nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532634(CHEMBL4451530)
Affinity DataIC50: 157nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532621(CHEMBL4556479)
Affinity DataIC50: 166nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532621(CHEMBL4556479)
Affinity DataIC50: 166nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532630(CHEMBL4561771)
Affinity DataIC50: 3.48E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532630(CHEMBL4561771)
Affinity DataIC50: 3.48E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532625(CHEMBL4468083)
Affinity DataIC50: 3.62E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532625(CHEMBL4468083)
Affinity DataIC50: 3.62E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532619(CHEMBL4568245)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CDK8 in IFN-gamma-induced human HCT116 cells assessed as suppression of STAT1 phosphorylation at serine727 residue incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532619(CHEMBL4568245)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CDK8 in IFN-gamma-induced human HCT116 cells assessed as suppression of STAT1 phosphorylation at serine727 residue incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532627(CHEMBL4514427)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CDK8 in IFN-gamma-induced human HCT116 cells assessed as suppression of STAT1 phosphorylation at serine727 residue incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532627(CHEMBL4514427)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CDK8 in IFN-gamma-induced human HCT116 cells assessed as suppression of STAT1 phosphorylation at serine727 residue incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532626(CHEMBL4553528)
Affinity DataIC50: 5.01E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532626(CHEMBL4553528)
Affinity DataIC50: 5.01E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532618(CHEMBL4435709)
Affinity DataIC50: 7.16E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532618(CHEMBL4435709)
Affinity DataIC50: 7.16E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
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