Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50047690
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183383(CHEMBL3818547)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183406(CHEMBL3818062)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183391(CHEMBL3818563)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183395(CHEMBL3818289)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183383(CHEMBL3818547)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183400(CHEMBL3818364)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183387(CHEMBL3818115)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183406(CHEMBL3818062)
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183407(CHEMBL3819553)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183395(CHEMBL3818289)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183400(CHEMBL3818364)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183391(CHEMBL3818563)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183387(CHEMBL3818115)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183394(CHEMBL3819120)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183407(CHEMBL3819553)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183383(CHEMBL3818547)
Affinity DataIC50: 26nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183394(CHEMBL3819120)
Affinity DataIC50: 26nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183393(CHEMBL3818970)
Affinity DataIC50: 38nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183406(CHEMBL3818062)
Affinity DataIC50: 40nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183393(CHEMBL3818970)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183387(CHEMBL3818115)
Affinity DataIC50: 53nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183395(CHEMBL3818289)
Affinity DataIC50: 59nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 76nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183393(CHEMBL3818970)
Affinity DataIC50: 81nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183400(CHEMBL3818364)
Affinity DataIC50: 111nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50: 126nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 173nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183407(CHEMBL3819553)
Affinity DataIC50: 295nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183394(CHEMBL3819120)
Affinity DataIC50: 333nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183391(CHEMBL3818563)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed