Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50047736
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50186972(CHEMBL3823127)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187106(CHEMBL3823992)
Affinity DataIC50: 3nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50186971(CHEMBL3823882)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187108(CHEMBL3822845)
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187107(CHEMBL3822712)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50186972(CHEMBL3823127)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187038(CHEMBL3823000)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187032(CHEMBL3822889)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187058(CHEMBL3823892)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187114(CHEMBL3823303)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant FLAG-tagged TAK1 kinase domain (unknown origin) expressed in baculovirus expression system coexpressing TAB using biotin-la...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50042034(CHEMBL1077979 | CHEBI:67559 | (5Z)-7-Oxozeaenol | ...)
Affinity DataIC50: 9nMAssay Description:Inhibition of full length TAK1 (unknown origin) fused with TAB1 using biotin-MKK6 as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187109(CHEMBL3822535)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187111(CHEMBL3823738)
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187110(CHEMBL3823335)
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187070(CHEMBL3824212)
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50186814(CHEMBL3823018)
Affinity DataIC50: 41nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187113(CHEMBL3824153)
Affinity DataIC50: 50nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187115(CHEMBL3822835)
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant TAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187036(CHEMBL3823067)
Affinity DataIC50: 220nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187118(CHEMBL3822673)
Affinity DataIC50: 260nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187116(CHEMBL3822538)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187117(CHEMBL3822610)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187112(CHEMBL3823800)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant TAK1 fused with TAB1 using MKK6 as substrate in presence of gamma-[33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50187111(CHEMBL3823738)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed