Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50047738
Target5-hydroxytryptamine receptor 2A(Rat)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50017721(5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclop...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097224(1-Methyl-4-thioxanthen-9-ylidene-piperidine | Pime...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097222(4-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097215(4-Fluoren-9-ylidene-1-methyl-piperidine | CHEMBL34...)
Affinity DataKi:  199nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50017721(5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclop...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097224(1-Methyl-4-thioxanthen-9-ylidene-piperidine | Pime...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097216(1-Methyl-4-xanthen-9-ylidene-piperidine | CHEMBL15...)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097215(4-Fluoren-9-ylidene-1-methyl-piperidine | CHEMBL34...)
Affinity DataIC50: 4.15E+4nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097222(4-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene...)
Affinity DataIC50: 5.91E+4nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097226(4-Benzhydrylidene-1-methyl-piperidine | CHEMBL3475...)
Affinity DataIC50: 9.46E+4nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50187207(CHEMBL3827431)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50187208(CHEMBL3827386)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50187211(CHEMBL20468)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50187212(CHEMBL3828393)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50187209(CHEMBL3828123)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50187210(CHEMBL3827652)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed