Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50048170
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442991(GNF-Pf-3777 | CHEMBL432537 | US10669273, Compound ...)
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442991(GNF-Pf-3777 | CHEMBL432537 | US10669273, Compound ...)
Affinity DataKi:  970nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM48009(SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442991(GNF-Pf-3777 | CHEMBL432537 | US10669273, Compound ...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442987(8-Bromotryptanthrin | CHEMBL72165)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM48009(SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...)
Affinity DataKi:  3.50E+3nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442987(8-Bromotryptanthrin | CHEMBL72165)
Affinity DataKi:  5.60E+3nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM48009(SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442988(CHEMBL3087009)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442987(8-Bromotryptanthrin | CHEMBL72165)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442988(CHEMBL3087009)
Affinity DataKi:  1.32E+4nMAssay Description:Mixed competitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...)
Affinity DataKi:  1.52E+4nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442990(CHEMBL1276265)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442989(CHEMBL3087010)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442988(CHEMBL3087009)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442994(CHEMBL312537 | US10669273, Compound 5b)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442989(CHEMBL3087010)
Affinity DataKi:  2.46E+4nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442994(CHEMBL312537 | US10669273, Compound 5b)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442994(CHEMBL312537 | US10669273, Compound 5b)
Affinity DataKi:  3.46E+4nMAssay Description:Non-competitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442995(CHEMBL3086870)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442990(CHEMBL1276265)
Affinity DataKi:  3.95E+4nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442989(CHEMBL3087010)
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442995(CHEMBL3086870)
Affinity DataIC50: 5.68E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50241727(L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...)
Affinity DataIC50: 5.69E+4nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442990(CHEMBL1276265)
Affinity DataIC50: 6.79E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50241727(L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...)
Affinity DataIC50: 8.25E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442995(CHEMBL3086870)
Affinity DataKi:  1.05E+5nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50207089(D-1-Methyltryptophan | D-1MT | Indoximod)
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50207089(D-1-Methyltryptophan | D-1MT | Indoximod)
Affinity DataIC50: 2.63E+5nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50241727(L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition of recombinant human IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynurenine formation using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50241727(L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...)
Affinity DataKi:  4.25E+5nMAssay Description:Competitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of vary...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50207089(D-1-Methyltryptophan | D-1MT | Indoximod)
Affinity DataKi:  3.30E+6nMAssay Description:Inhibition of recombinant human IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynurenine formation using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2018
Entry Details Article
PubMed