Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50018888
TargetAcetylcholinesterase(Electric eel)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50613668(CHEMBL479289)
Affinity DataIC50: 8.47E+3nMAssay Description:Inhibition of electric eel AChE (type VI-S) using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by El...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50228072(1,9-dihydroxy-3-(1',1'-dimethylheptyl)-6H-benzo[c]...)
Affinity DataKi:  0.820nMAssay Description:Binding affinity to CB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50061116(3-(1,1-Dimethyl-heptyl)-1-hydroxy-9-methyl-benzo[c...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to CB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50228073(AM-1710 | 3-(1',1'-dimethylheptyl)-1-hydroxy-9-met...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity to CB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50218528(AP-2243 | 3-{4-[(benzylethylamino)methyl]phenyl}-6...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human AChE assessed as hydrolysis of acetylthiocholine by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50218513(3-(4-{[benzyl-(2-hydroxyethyl)amino]methyl}phenyl)...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human AChE assessed as hydrolysis of acetylthiocholine by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50218515(benzyl-[4-(6,7-dimethoxy-2-oxo-2H-chromen-3-yl)ben...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human AChE assessed as hydrolysis of acetylthiocholine by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Minho

Curated by ChEMBL
LigandPNGBDBM10949(CHEMBL75121 | 3-(4-{[benzyl(methyl)amino]methyl}ph...)
Affinity DataKi:  45nMAssay Description:Inhibition of recombinant human AChE assessed as hydrolysis of acetylthiocholine by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50613669(CHEMBL5276321)
Affinity DataKi:  47nMAssay Description:Binding affinity to rat 5-HT1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50613668(CHEMBL479289)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of electric eel acetyl cholinesterase measured for 3 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Minho

Curated by ChEMBL
LigandPNGBDBM50613668(CHEMBL479289)
Affinity DataKi:  3.43E+3nMAssay Description:Inhibition of electric eel AChE (type VI-S) using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by El...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed