Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50047824
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191945(CHEMBL3904768)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191977(CHEMBL3983564)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191981(CHEMBL3979322)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191973(CHEMBL3940697)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191974(CHEMBL3913766)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191975(CHEMBL3975580)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191946(CHEMBL3950278)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191980(CHEMBL3985689)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192005(CHEMBL3947262)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191972(CHEMBL3895824)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192006(CHEMBL3955987)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192007(CHEMBL3902237)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191973(CHEMBL3940697)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191975(CHEMBL3975580)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191945(CHEMBL3904768)
Affinity DataIC50: 3nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191976(CHEMBL3967097)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191974(CHEMBL3913766)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191946(CHEMBL3950278)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191972(CHEMBL3895824)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191981(CHEMBL3979322)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192006(CHEMBL3955987)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192005(CHEMBL3947262)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191979(CHEMBL3906976)
Affinity DataIC50: 12nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 13nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192008(CHEMBL3971140)
Affinity DataIC50: 13nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191977(CHEMBL3983564)
Affinity DataIC50: 19nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192007(CHEMBL3902237)
Affinity DataIC50: 22nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191976(CHEMBL3967097)
Affinity DataIC50: 23nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191980(CHEMBL3985689)
Affinity DataIC50: 35nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50192008(CHEMBL3971140)
Affinity DataIC50: 36nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 162nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191981(CHEMBL3979322)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of M1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed