Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50010247
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Anhui Agricultural University
Curated by ChEMBL
Anhui Agricultural University
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged C-terminal His6-tagged MEK1 expressed in Escherichia coli using myelin basic protei...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Anhui Agricultural University
Curated by ChEMBL
Anhui Agricultural University
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged C-terminal His6-tagged MEK1 expressed in Escherichia coli using myelin basic protei...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Anhui Agricultural University
Curated by ChEMBL
Anhui Agricultural University
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of MEK1 in BRAF mutant human A549 cells assessed as reduction in ERK1/2 phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of FAK in human MCF7 cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Anhui Agricultural University
Curated by ChEMBL
Anhui Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
