Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50048117
TargetCysteine protease ATG4B(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM80861(4-[2-(2-cyclohexyl-5,6-dimethylthieno[2,3-d]pyrimi...)
Affinity DataIC50: 316nMAssay Description:Inhibition of wild type recombinant Atg4B (unknown origin) expressed in Escherichia coli BL21 DE3 using N-terminal His6-tagged LC3B-PLA2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50085339(((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid...)
Affinity DataIC50: 630nMAssay Description:Inhibition of Atg4B (unknown origin) using YFP-LC3B-EmGFP as substrate after 40 mins by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Atg4B (unknown origin) using YFP-LC3B-EmGFP as substrate after 40 mins by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of wild type recombinant Atg4B (unknown origin) expressed in Escherichia coli BL21 DE3 using N-terminal His6-tagged LC3B-PLA2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of wild type recombinant Atg4B (unknown origin) expressed in Escherichia coli BL21 DE3 using N-terminal His6-tagged LC3B-PLA2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human recombinant GST-tagged Atg4B expressed in Escherichia coli using LC3B-GST as substrate after 6 mins by SDS-PAGE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM34545(MLS000104342 | N-pyridin-2-ylpyridine-2-carbothioa...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Atg4B (unknown origin) using LC3B-GST as substrate preincubated for 24 hrs followed by substrate addition measured for 3 mins by SDS-PA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50060874(hipericina | hypericine | hypericum red | 1,3,4,6,...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of Atg4B (unknown origin) using YFP-LC3B-EmGFP as substrate after 40 mins by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed