Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018893
TargetCyclin-dependent kinase 1(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50613673(CHEMBL1964259)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human CDK1 using Biotinaminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2 peptide as substrate incubated for 20 to 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM10112((3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methyli...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM10109((3Z)-4-[(3R,4S,5R)-4-amino-3,5-dihydroxyhex-1-yn-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50132450(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human Syk expressed in Kluyveromyces lactis using Biot-(BA)3-DEEYEIP-NH2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366929(CHEMBL1794057)
Affinity DataIC50: 7nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50613675(CHEMBL5275659)
Affinity DataIC50: 8nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50085415(G6416 (GW5074) | 3-(3,5-dibromo-4-hydroxybenzylide...)
Affinity DataIC50: 9nMAssay Description:Inhibition of cRAF1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50613673(CHEMBL1964259)
Affinity DataIC50: 12nMAssay Description:Inhibition of human CDK2 g-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2 peptide as substrate incubated for 30 to 60 mins by scintillation counter analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProgesterone receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50121167(5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProgesterone receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50121177(3-Methyl-5-(3-nitro-phenyl)-1,3-dihydro-indol-2-on...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProgesterone receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50121158(5'-(3-chlorophenyl)spiro[cyclopentane-1,3'-indol]-...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50366930(CHEMBL1794059)
Affinity DataIC50: 63nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProgesterone receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50121162(5'-(3-chlorophenyl)spiro[cyclopropane-1,3'-indol]-...)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50613676(CHEMBL5278067)
Affinity DataIC50: 96nMAssay Description:Inhibition of VEGFR1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50132451(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50:  100nMAssay Description:Inhibition of human Syk expressed in Kluyveromyces lactis using Biot-(BA)3-DEEYEIP-NH2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProgesterone receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50121168(3,3-Dimethyl-5-(3-nitro-phenyl)-1,3-dihydro-indol-...)
Affinity DataIC50: 102nMAssay Description:Antagonist activity at progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50132451(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataIC50: 145nMAssay Description:Inhibition of human Syk expressed in Kluyveromyces lactis using Biot-(BA)3-DEEYEIP-NH2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50613674(CHEMBL1952030)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of recombinant human CDK2 in presence of ATP by FlashPlate assaysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50613678(CHEMBL3633197)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of AR (unknown origin) assessed as glycation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50613677(CHEMBL5284180)
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibition of AR (unknown origin) assessed as glycation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50217942(3-Rhamnoglucosylquercetin | cid_5280805 | CHEMBL22...)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of AR (unknown origin) assessed as glycation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed