Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50010087
TargetAdenosine 5'-monophosphoramidase HINT1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50535044(CHEMBL4471567)
Affinity DataKd:  230nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine 5'-monophosphoramidase HINT1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119454(CHEMBL3140272)
Affinity DataKd:  320nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50535045(CHEMBL4455776)
Affinity DataKd:  810nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50535046(CHEMBL4549820)
Affinity DataKd:  920nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119454(CHEMBL3140272)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells using TrpAMP as substrate measured for 2 to 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50535047(CHEMBL4468179)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360481(CHEMBL1934757)
Affinity DataKd:  3.65E+3nMAssay Description:Binding affinity to recombinant human HINT1 by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360481(CHEMBL1934757)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells using TrpAMP as substrate measured for 2 to 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed