Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50048261
TargetCytochrome P450 1B1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in bacterial microsomes co-expressing P450 reductase using 7-ethyl-O-resorufin as substrate after 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1B1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50210692(CHEMBL3971601)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in bacterial microsomes co-expressing P450 reductase using 7-ethyl-O-resorufin as substrate after 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM17289(folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in bacterial microsomes co-expressing P450 reductase using 7-ethyl-O-resorufin as substrate after 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in bacterial microsomes co-expressing P450 reductase using 7-ethyl-O-resorufin as substrate after 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed