Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 50000713
TargetD(3) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259267(CHEMBL4099779)
Affinity DataKi:  0.5nMAssay Description:Antagonist activity at D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325744(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)q...)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325748(N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)...)
Affinity DataKi:  1nMAssay Description:Antagonist activity at D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325746(N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)isoq...)
Affinity DataKi:  1nMAssay Description:Antagonist activity at D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259291(CHEMBL4102970)
Affinity DataKi:  2.70nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259291(CHEMBL4102970)
Affinity DataKi:  2.70nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259290(CHEMBL4078910)
Affinity DataKi:  2.80nMAssay Description:Antagonist activity at D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259257(CHEMBL4065099)
Affinity DataKi:  3nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259257(CHEMBL4065099)
Affinity DataKi:  3nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325747(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)i...)
Affinity DataKi:  3.10nMAssay Description:Antagonist activity at D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259258(CHEMBL4098585)
Affinity DataKi:  4nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259258(CHEMBL4098585)
Affinity DataKi:  4nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259268(CHEMBL4084820)
Affinity DataKi:  4.80nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325747(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)i...)
Affinity DataKi:  5.20nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325747(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)i...)
Affinity DataKi:  5.20nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325748(N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)...)
Affinity DataKi:  5.40nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325748(N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)...)
Affinity DataKi:  5.40nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259293(CHEMBL4063170)
Affinity DataKi:  8.30nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259291(CHEMBL4102970)
Affinity DataKi:  9.60nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325744(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)q...)
Affinity DataKi:  10nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259293(CHEMBL4063170)
Affinity DataKi:  11nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259293(CHEMBL4063170)
Affinity DataKi:  11nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259257(CHEMBL4065099)
Affinity DataKi:  14nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259249(CHEMBL4095224)
Affinity DataKi:  14nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259249(CHEMBL4095224)
Affinity DataKi:  15nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259265(CHEMBL4082297)
Affinity DataKi:  19nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259265(CHEMBL4082297)
Affinity DataKi:  19nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259250(CHEMBL4062122)
Affinity DataKi:  22nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50198913(CHEMBL1179089)
Affinity DataKi:  24nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50198913(CHEMBL1179089)
Affinity DataKi:  25nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50198913(CHEMBL1179089)
Affinity DataKi:  25nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259264(CHEMBL4100315)
Affinity DataKi:  27nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259264(CHEMBL4100315)
Affinity DataKi:  27nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325747(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)i...)
Affinity DataKi:  30nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50050165(4-(4-Iodo-phenyl)-butyric acid 3-(1H-imidazol-4-yl...)
Affinity DataKi:  41nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259258(CHEMBL4098585)
Affinity DataKi:  47nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325746(N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)isoq...)
Affinity DataKi:  51nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325746(N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)isoq...)
Affinity DataKi:  51nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259292(CHEMBL4084275)
Affinity DataKi:  62nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259292(CHEMBL4084275)
Affinity DataKi:  62nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50050165(4-(4-Iodo-phenyl)-butyric acid 3-(1H-imidazol-4-yl...)
Affinity DataKi:  118nMAssay Description:Antagonist activity at human H4 receptor expressed in CHO cells co-expressing Galphai2 assessed as inhibition of imetit-induced GTPgamma[35S] binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259264(CHEMBL4100315)
Affinity DataKi:  118nMAssay Description:Antagonist activity at H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50050165(4-(4-Iodo-phenyl)-butyric acid 3-(1H-imidazol-4-yl...)
Affinity DataKi:  118nMAssay Description:Antagonist activity at H4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325744(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)q...)
Affinity DataKi:  125nMAssay Description:Antagonist activity at human H4 receptor expressed in CHO cells co-expressing Galphai2 assessed as inhibition of imetit-induced GTPgamma[35S] binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50325744(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)q...)
Affinity DataKi:  125nMAssay Description:Antagonist activity at H4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259251(CHEMBL4083336)
Affinity DataKi:  174nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259251(CHEMBL4083336)
Affinity DataKi:  174nMAssay Description:Antagonist activity at H4 receptor in human SH-SY5Y cells assessed as inhibition of imetit-induced GTPgamma[35S] binding after 30 mins by microbeta s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259266(CHEMBL4102243)
Affinity DataKi:  214nMAssay Description:Antagonist activity at H4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50259266(CHEMBL4102243)
Affinity DataKi:  214nMAssay Description:Antagonist activity at human H4 receptor expressed in CHO cells co-expressing Galphai2 assessed as inhibition of imetit-induced GTPgamma[35S] binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50146144(4-(3-Trityloxy-propyl)-1H-imidazole | CHEMBL91576)
Affinity DataKi:  240nMAssay Description:Antagonist activity at H4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details Article
PubMed
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