Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50000717
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 0.870nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 34.1nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 41.5nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 175nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 178nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 194nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50259592(CHEMBL4080255)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant GST-tagged c-Src (unknown origin) expressed in insect cells using pEY as substrate preincubated with enzyme followed by [33...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 224nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 468nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 551nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 589nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 4.41E+3nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 4.56E+3nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 7.46E+3nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed