Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50047997
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200480(CHEMBL3965352)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200480(CHEMBL3965352)
Affinity DataEC50:  24nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 50 nM measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200484(CHEMBL3960082)
Affinity DataIC50: 46nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200480(CHEMBL3965352)
Affinity DataEC50:  47nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 100 nM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200482(CHEMBL3978393)
Affinity DataIC50: 53nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200483(CHEMBL3979327)
Affinity DataIC50: 85nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200480(CHEMBL3965352)
Affinity DataEC50:  137nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 500 nM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200481(CHEMBL3986017)
Affinity DataIC50: 155nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200493(CHEMBL3951963)
Affinity DataIC50: 180nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200492(CHEMBL3933195)
Affinity DataIC50: 184nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200478(CHEMBL3967752)
Affinity DataIC50: 212nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200500(CHEMBL3968327)
Affinity DataIC50: 220nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200498(CHEMBL3924243)
Affinity DataIC50: 241nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200494(CHEMBL3980443)
Affinity DataIC50: 243nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200485(CHEMBL3941556)
Affinity DataIC50: 265nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200495(CHEMBL3949509)
Affinity DataIC50: 270nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200499(CHEMBL3932585)
Affinity DataIC50: 282nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200491(CHEMBL3971787)
Affinity DataIC50: 290nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200488(CHEMBL3890559)
Affinity DataIC50: 327nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200496(CHEMBL3977846)
Affinity DataIC50: 476nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200486(CHEMBL3976847)
Affinity DataIC50: 588nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200489(CHEMBL3959631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200475(CHEMBL3913172)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200487(CHEMBL3948161)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200501(CHEMBL3890551)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200490(CHEMBL3979853)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200476(CHEMBL3950902)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200477(CHEMBL3909304)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200479(CHEMBL3906154)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200481(CHEMBL3986017)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200480(CHEMBL3965352)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200498(CHEMBL3924243)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50200478(CHEMBL3967752)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed