Compile Data Set for Download or QSAR
Report error Found 211 Enz. Inhib. hit(s) with all data for entry = 50013234
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50386790(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
Affinity DataEC50:  0.350nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563845(CHEMBL4793371)
Affinity DataEC50:  0.420nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563848(CHEMBL4782004)
Affinity DataEC50:  0.460nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563860(CHEMBL4788206)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563845(CHEMBL4793371)
Affinity DataEC50:  0.540nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563858(CHEMBL4785057)
Affinity DataEC50:  0.590nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563860(CHEMBL4788206)
Affinity DataEC50:  0.590nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563848(CHEMBL4782004)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563857(CHEMBL4797858)
Affinity DataEC50:  0.620nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563849(CHEMBL4797124)
Affinity DataEC50:  0.690nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563857(CHEMBL4797858)
Affinity DataEC50:  0.830nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563843(CHEMBL4798993)
Affinity DataEC50:  0.830nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563846(CHEMBL4787010)
Affinity DataEC50:  0.830nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200369(CHEMBL3915620)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563854(CHEMBL4791842)
Affinity DataEC50:  0.880nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563858(CHEMBL4785057)
Affinity DataEC50:  0.890nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563848(CHEMBL4782004)
Affinity DataEC50:  0.930nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563849(CHEMBL4797124)
Affinity DataEC50:  0.980nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563843(CHEMBL4798993)
Affinity DataEC50:  1nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204012(CHEMBL3955132)
Affinity DataEC50:  1nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563846(CHEMBL4787010)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563846(CHEMBL4787010)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563846(CHEMBL4787010)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563849(CHEMBL4797124)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200369(CHEMBL3915620)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563856(CHEMBL4800563)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563842(CHEMBL4798023)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563863(CHEMBL4787498)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563854(CHEMBL4791842)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563842(CHEMBL4798023)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563845(CHEMBL4793371)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362690(CHEMBL1829173 | AMG-837)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563844(CHEMBL4781604)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563857(CHEMBL4797858)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563857(CHEMBL4797858)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563843(CHEMBL4798993)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362690(CHEMBL1829173 | AMG-837)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563847(CHEMBL4792075)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563845(CHEMBL4793371)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563863(CHEMBL4787498)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563846(CHEMBL4787010)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362690(CHEMBL1829173 | AMG-837)
Affinity DataKd:  1.90nMAssay Description:Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563848(CHEMBL4782004)
Affinity DataKd:  2nMAssay Description:Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200369(CHEMBL3915620)
Affinity DataEC50:  2nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563859(CHEMBL4786335)
Affinity DataEC50:  2nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563856(CHEMBL4800563)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563857(CHEMBL4797858)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563862(CHEMBL4799453)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563847(CHEMBL4792075)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563854(CHEMBL4791842)
Affinity DataKd:  2.20nMAssay Description:Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
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