Compile Data Set for Download or QSAR
Report error Found 109 Enz. Inhib. hit(s) with all data for entry = 50001937
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450752(CHEMBL4216513)
Affinity DataIC50: 0.191nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50065646(CHEMBL3087181)
Affinity DataIC50: 0.214nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 0.219nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450752(CHEMBL4216513)
Affinity DataIC50: 0.269nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50065646(CHEMBL3087181)
Affinity DataIC50: 0.275nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50102829(CHEMBL3356956)
Affinity DataIC50: 0.309nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50065646(CHEMBL3087181)
Affinity DataIC50: 0.363nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450752(CHEMBL4216513)
Affinity DataIC50: 0.562nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50102829(CHEMBL3356956)
Affinity DataIC50: 0.589nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM179950(US9133148, 3a)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant human full length MAGL expressed in HEK293 cells preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450707(CHEMBL4215558)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM26739(URB 597 | URB597 | CHEMBL184238 | 3-(3-carbamoylph...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of FAAH in Wistar rat brain membranes using [3H]-anandamide as substrate preincubated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM26739(URB 597 | URB597 | CHEMBL184238 | 3-(3-carbamoylph...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged/C-terminal Myc-His6 tagged FAAH2 (32 to 579 residues) expressed in COS7 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450750(CHEMBL4216931)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of rat brain microsomal FAAH using N-(2-hydroxyethyl)-4-pyren-1-yl-butanamide as substrate after 60 mins by RP HPLC based fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450760(CHEMBL4218592)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of Sprague-Dawley rat brain FAAH preincubated for 10 mins followed by [3H]-anandamide substrate addition after 30 mins by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM179929(US9133148, 1a)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of recombinant human full length MAGL expressed in HEK293 cells preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450755(CHEMBL2171701)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM179955(US9133148, 3f)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant human full length MAGL expressed in HEK293 cells preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM179950(US9133148, 3a)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of mouse MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450764(CHEMBL4218039)
Affinity DataIC50: 9nMAssay Description:Inhibition of CD1 mouse FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450754(CHEMBL4202707)
Affinity DataIC50: 10nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450758(CHEMBL4209606)
Affinity DataIC50: 11nMAssay Description:Inhibition of rat brain microsomal FAAH using N-(2-hydroxyethyl)-4-pyren-1-yl-butanamide as substrate after 60 mins by RP HPLC based fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM26736(N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1H-1,2,3,4...)
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse brain membrane FAAH preincubated for 10 mins followed by 14C-oleamide substrate addition measured up to 60 mins by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM23120(CHEMBL177577 | 7-phenyl-1-[5-(pyridin-2-yl)-1,3-ox...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged/C-terminal Myc-His6 tagged FAAH2 (32 to 579 residues) expressed in COS7 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50396293(CHEMBL94809)
Affinity DataIC50: 13nMAssay Description:Inhibition of Sprague-Dawley rat brain FAAH using [14C]anandamide as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM179950(US9133148, 3a)
Affinity DataIC50: 14nMAssay Description:Inhibition of rat MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM179929(US9133148, 1a)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM26740(N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carbo...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human N-terminal -His6 tagged FAAH (32 to 579 residues) expressed in Escherichia coli BL21 preincubated for 60 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450762(CHEMBL4213655)
Affinity DataIC50: 26nMAssay Description:Inhibition of Sprague-Dawley rat brain FAAH preincubated for 10 mins followed by [3H]-anandamide substrate addition after 30 mins by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50128585(CHEMBL431202 | Cyclohexyl-carbamic acid biphenyl-3...)
Affinity DataIC50: 26nMAssay Description:Inhibition of FAAH in Wistar rat brain membranes using [3H]-anandamide as substrate preincubated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50437227(CHEMBL2402927 | US9187413, 1b (URB937))
Affinity DataIC50: 27nMAssay Description:Inhibition of FAAH in Wistar rat brain membranes using [3H]-anandamide as substrate preincubated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 27nMAssay Description:Inhibition recombinant human NAAA expressed in HEK293 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450707(CHEMBL4215558)
Affinity DataIC50: 29nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM97458(FAAH Inhibitor, 2g)
Affinity DataIC50: 30nMAssay Description:Inhibition of FAAH in Wistar rat brain membranes using [3H]-anandamide as substrate preincubated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM393301(US9963444, Example 4 | (10-Isothiocyanatodecyl)ben...)
Affinity DataIC50: 30nMAssay Description:Inhibition of NAAA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM26741(N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carbo...)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human N-terminal -His6 tagged FAAH (32 to 579 residues) expressed in Escherichia coli BL21 preincubated for 60 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50242634(5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazol...)
Affinity DataIC50: 33nMAssay Description:Inhibition of FAAH in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM179938(US9133148, 2b)
Affinity DataIC50: 38nMAssay Description:Inhibition of mouse MAGL after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450761(CHEMBL4202705)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM179929(US9133148, 1a)
Affinity DataIC50: 43nMAssay Description:Inhibition of rat MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM233796(US9353075, 53)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells preincubated for 10 mins followed by PAMCA substrate addition after 30 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Sprague-Dawley rat NAAA expressed in HEK293 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450757(CHEMBL4204739)
Affinity DataIC50: 81nMAssay Description:Inhibition of rat brain microsomal FAAH using N-(2-hydroxyethyl)-4-pyren-1-yl-butanamide as substrate after 60 mins by RP HPLC based fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450765(CHEMBL4209559)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human MAGL preincubated for 10 mins followed by 2-AG substrate addition after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50414921(CHEMBL570812)
Affinity DataIC50: 86nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM66023(2-octyl-1,2-thiazol-3-one | cid_33528 | 2-octyl-3-...)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50414921(CHEMBL570812)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50450775(CHEMBL4207055 | med.21724, Compound 142)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant rat MAGL expressed in Escherichia coli using 2-AG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
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