Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50010003
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534343(CHEMBL4529036)
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534347(CHEMBL4476253)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534337(CHEMBL4566086)
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534342(CHEMBL4441146)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC8 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534341(CHEMBL4526387)
Affinity DataIC50: 133nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534346(CHEMBL4530273)
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534340(CHEMBL4591041)
Affinity DataIC50: 464nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in sf9 cells using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534345(CHEMBL4550619)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534344(CHEMBL4450063)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in sf9 cells using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus expression system using fluorophore-conjugated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534348(CHEMBL4471751)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus expression system using fluorophore-conjugated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged HDAC3 expressed in sf9 cells co-expressing human N-terminal GST-tagged NCOR2 (395 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in sf9 cells using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in sf9 cells using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534338(CHEMBL4534486)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged HDAC3 expressed in sf9 cells co-expressing human N-terminal GST-tagged NCOR2 (395 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed