Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50048101
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204536(CHEMBL3984105)
Affinity DataIC50: 26nMAssay Description:Inhibition of Orai1 (unknown origin) by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204536(CHEMBL3984105)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204544(CHEMBL262766)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM31773(ECONAZOLE | cid_68589 | Pevaryl | Gyno-pevaryl | E...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM31772(Brentan | 1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dich...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204538(CHEMBL3913392)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction of SERCA inhibition-induced ER release preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204541(CHEMBL3942942)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50117922(CHEMBL45816 | Methoxy-acetic acid 2-(2-{[3-(1H-ben...)
Affinity DataIC50: 5.21E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction of SERCA inhibition-induced ER release preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204537(CHEMBL100350)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204538(CHEMBL3913392)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204540(CHEMBL3907105)
Affinity DataIC50: 6.99E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204543(CHEMBL1545070)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM31773(ECONAZOLE | cid_68589 | Pevaryl | Gyno-pevaryl | E...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction of SERCA inhibition-induced ER release preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM31772(Brentan | 1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dich...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction of SERCA inhibition-induced ER release preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50117922(CHEMBL45816 | Methoxy-acetic acid 2-(2-{[3-(1H-ben...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204535(CHEMBL3972536)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetCalcium release-activated calcium channel protein 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50204535(CHEMBL3972536)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction of SERCA inhibition-induced ER release preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed