Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50048977
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 24nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232320(CHEMBL4103370)
Affinity DataIC50: 81nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232320(CHEMBL4103370)
Affinity DataIC50: 81nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232327(CHEMBL4084249)
Affinity DataIC50: 98nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232327(CHEMBL4084249)
Affinity DataIC50: 98nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232320(CHEMBL4103370)
Affinity DataIC50: 610nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232327(CHEMBL4084249)
Affinity DataIC50: 910nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232328(CHEMBL4084996)
Affinity DataIC50: 979nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232328(CHEMBL4084996)
Affinity DataIC50: 980nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232328(CHEMBL4084996)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232321(CHEMBL4079125)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232321(CHEMBL4079125)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232324(CHEMBL4094471)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232324(CHEMBL4094471)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232321(CHEMBL4079125)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232344(CHEMBL4066118)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232344(CHEMBL4066118)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232324(CHEMBL4094471)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232344(CHEMBL4066118)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232322(CHEMBL4095623)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232322(CHEMBL4095623)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232330(CHEMBL4068254)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232330(CHEMBL4068254)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232319(CHEMBL4083493)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232319(CHEMBL4083493)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232322(CHEMBL4095623)
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232325(CHEMBL4074782)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232325(CHEMBL4074782)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232330(CHEMBL4068254)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232326(CHEMBL4102214)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232326(CHEMBL4102214)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232329(CHEMBL4102942)
Affinity DataIC50: 4.51E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232329(CHEMBL4102942)
Affinity DataIC50: 4.51E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232319(CHEMBL4083493)
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232323(CHEMBL4087921)
Affinity DataIC50: 4.63E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232323(CHEMBL4087921)
Affinity DataIC50: 4.63E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232325(CHEMBL4074782)
Affinity DataIC50: 4.68E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232343(CHEMBL4095195)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232343(CHEMBL4095195)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232323(CHEMBL4087921)
Affinity DataIC50: 5.24E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232329(CHEMBL4102942)
Affinity DataIC50: 5.26E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232326(CHEMBL4102214)
Affinity DataIC50: 5.76E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232341(CHEMBL4065301)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232341(CHEMBL4065301)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232336(CHEMBL4068814)
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232336(CHEMBL4068814)
Affinity DataIC50: 6.55E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232337(CHEMBL4094647)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232337(CHEMBL4094647)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232345(CHEMBL4074726)
Affinity DataIC50: 7.35E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
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