Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50000738
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259919(CHEMBL4080813)
Affinity DataEC50:  26nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259919(CHEMBL4080813)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259938(CHEMBL4104136)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259921(CHEMBL4086223)
Affinity DataEC50:  35nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259915(CHEMBL4063687)
Affinity DataIC50: 38nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259914(CHEMBL4060728)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259947(CHEMBL4085299)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259938(CHEMBL4104136)
Affinity DataEC50:  53nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259916(CHEMBL4067446)
Affinity DataEC50:  56nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259923(CHEMBL4078355)
Affinity DataEC50:  62nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259915(CHEMBL4063687)
Affinity DataEC50:  120nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259925(CHEMBL4077127)
Affinity DataEC50:  140nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259918(CHEMBL4105038)
Affinity DataEC50:  150nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259914(CHEMBL4060728)
Affinity DataEC50:  170nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259919(CHEMBL4080813)
Affinity DataEC50:  200nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells co-expressing human RIC-3 assessed as area under current curve at holding potential of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259936(CHEMBL4077622)
Affinity DataEC50:  290nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259944(CHEMBL4076554)
Affinity DataEC50:  490nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259921(CHEMBL4086223)
Affinity DataEC50:  500nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells co-expressing human RIC-3 assessed as area under current curve at holding potential of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259924(CHEMBL4096397)
Affinity DataEC50:  530nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259913(CHEMBL4082605)
Affinity DataEC50:  550nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259936(CHEMBL4077622)
Affinity DataIC50: 620nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259947(CHEMBL4085299)
Affinity DataEC50:  750nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259937(CHEMBL4081582)
Affinity DataIC50: 860nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259917(CHEMBL4088682)
Affinity DataEC50:  880nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259945(CHEMBL4093984)
Affinity DataEC50:  990nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259936(CHEMBL4077622)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells co-expressing human RIC-3 assessed as area under current curve at holding potential of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259918(CHEMBL4105038)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells co-expressing human RIC-3 assessed as area under current curve at holding potential of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259937(CHEMBL4081582)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259914(CHEMBL4060728)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells co-expressing human RIC-3 assessed as area under current curve at holding potential of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259926(CHEMBL4066441)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259944(CHEMBL4076554)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259945(CHEMBL4093984)
Affinity DataIC50: 5.60E+3nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259925(CHEMBL4077127)
Affinity DataIC50: 6.40E+3nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259921(CHEMBL4086223)
Affinity DataIC50: 7.40E+3nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259946(CHEMBL4069408)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259946(CHEMBL4069408)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259913(CHEMBL4082605)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259924(CHEMBL4096397)
Affinity DataIC50: 1.45E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259918(CHEMBL4105038)
Affinity DataIC50: 1.80E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259917(CHEMBL4088682)
Affinity DataIC50: 3.20E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259916(CHEMBL4067446)
Affinity DataIC50: 3.20E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259923(CHEMBL4078355)
Affinity DataIC50: 3.80E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50259926(CHEMBL4066441)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed