Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50048026
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201564(CHEMBL3890777)
Affinity DataKd:  19nMAssay Description:Binding affinity to recombinant human C-terminal 6His-tagged/biotinylated complement factor D (26 to 253 residues) expressed in Sf9 insect cells by b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201565(CHEMBL3941259)
Affinity DataKd:  17nMAssay Description:Binding affinity to recombinant human C-terminal 6His-tagged/biotinylated complement factor D (26 to 253 residues) expressed in Sf9 insect cells by b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201569(CHEMBL3924715)
Affinity DataKd:  2.21E+3nMAssay Description:Binding affinity to recombinant human C-terminal 6His-tagged/biotinylated complement factor D (26 to 253 residues) expressed in Sf9 insect cells by b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201568(CHEMBL3951127)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to recombinant human C-terminal 6His-tagged/biotinylated complement factor D (26 to 253 residues) expressed in Sf9 insect cells by b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201564(CHEMBL3890777)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human C-terminal 6His-tagged complement factor D (26 to 253 residues) expressed in Sf9 insect cells preincubated for 1 hr f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201568(CHEMBL3951127)
Affinity DataIC50: 19nMAssay Description:Inhibition of human serum factor D-mediated complement activation in rabbit erythrocytes assessed as reduction in rabbit erythrocyte hemolysis preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201564(CHEMBL3890777)
Affinity DataIC50: 27nMAssay Description:Competitive inhibition of human complement factor D preincubated for 1 hr followed by addition of Z-Lys-thiobenzyl ester as substrate measured over 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201565(CHEMBL3941259)
Affinity DataIC50: 32nMAssay Description:Competitive inhibition of human complement factor D preincubated for 1 hr followed by addition of Z-Lys-thiobenzyl ester as substrate measured over 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201565(CHEMBL3941259)
Affinity DataIC50: 47nMAssay Description:Inhibition of human serum factor D-mediated complement activation in rabbit erythrocytes assessed as reduction in rabbit erythrocyte hemolysis preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201569(CHEMBL3924715)
Affinity DataIC50: 77nMAssay Description:Inhibition of human serum factor D-mediated complement activation in rabbit erythrocytes assessed as reduction in rabbit erythrocyte hemolysis preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201566(CHEMBL2220483)
Affinity DataIC50: 98nMAssay Description:Binding affinity to complement factor D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201564(CHEMBL3890777)
Affinity DataIC50: 205nMAssay Description:Inhibition of human serum factor D-mediated complement activation in rabbit erythrocytes assessed as reduction in rabbit erythrocyte hemolysis preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201569(CHEMBL3924715)
Affinity DataIC50: 2.18E+3nMAssay Description:Competitive inhibition of human complement factor D preincubated for 1 hr followed by addition of Z-Lys-thiobenzyl ester as substrate measured over 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201570(CHEMBL346059 | US11584714, Compound 26# | US121954...)
Affinity DataIC50: 2.90E+3nMAssay Description:Binding affinity to complement factor D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201567(CHEMBL3901198)
Affinity DataIC50: 3.70E+3nMAssay Description:Binding affinity to complement factor D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed
TargetComplement factor D(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50201568(CHEMBL3951127)
Affinity DataIC50: 6.60E+3nMAssay Description:Competitive inhibition of human complement factor D preincubated for 1 hr followed by addition of Z-Lys-thiobenzyl ester as substrate measured over 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2018
Entry Details Article
PubMed