Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50048033
LigandPNGBDBM50323728(2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazo...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50323728(2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazo...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PI3Kdelta (unknown origin) in presence of [gamma-32P]ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201717(CHEMBL3907591)
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201728(CHEMBL3914552)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201716(CHEMBL3942550)
Affinity DataIC50: 7nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201720(CHEMBL3896635)
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201721(CHEMBL3964073)
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388180(CHEMBL2057912)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of BTK (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201723(CHEMBL3905578)
Affinity DataIC50: 9nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201721(CHEMBL3964073)
Affinity DataIC50: 12nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201727(CHEMBL3924678)
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201729(CHEMBL3923573)
Affinity DataIC50: 14nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50: 24nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50: 24nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201717(CHEMBL3907591)
Affinity DataIC50: 27nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201724(CHEMBL3983045)
Affinity DataIC50: 32nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50323728(2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazo...)
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kgamma (unknown origin) in presence of [gamma-32P]ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201729(CHEMBL3923573)
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201725(CHEMBL3948373)
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201719(CHEMBL3957821)
Affinity DataIC50: 43nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201718(CHEMBL3925929)
Affinity DataIC50: 55nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201718(CHEMBL3925929)
Affinity DataIC50: 55nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201716(CHEMBL3942550)
Affinity DataIC50: 61nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201720(CHEMBL3896635)
Affinity DataIC50: 67nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201724(CHEMBL3983045)
Affinity DataIC50: 84nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201723(CHEMBL3905578)
Affinity DataIC50: 86nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201725(CHEMBL3948373)
Affinity DataIC50: 104nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201728(CHEMBL3914552)
Affinity DataIC50: 142nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201719(CHEMBL3957821)
Affinity DataIC50: 172nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201718(CHEMBL3925929)
Affinity DataIC50: 176nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201718(CHEMBL3925929)
Affinity DataIC50: 176nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201727(CHEMBL3924678)
Affinity DataIC50: 217nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201715(CHEMBL3920744)
Affinity DataIC50: 584nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201730(CHEMBL3892739)
Affinity DataIC50: 891nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201730(CHEMBL3892739)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201715(CHEMBL3920744)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50201722(CHEMBL3977335)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50201722(CHEMBL3977335)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50323728(2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed