Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 7945
TargetTyrosine-protein kinase BTK(Human)
X-Chem Pharmaceuticals

LigandPNGBDBM225238(BTK inhibitor, 3)
Affinity DataIC50: 0.550nMT: 2°CAssay Description:The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
X-Chem Pharmaceuticals

LigandPNGBDBM225237(BTK inhibitor, 2)
Affinity DataIC50: 210nMT: 2°CAssay Description:The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
X-Chem Pharmaceuticals

LigandPNGBDBM225236(BTK inhibitor, 1)
Affinity DataIC50: 2.50E+3nMT: 2°CAssay Description:The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details Article
PubMed