Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50049014
TargetCytochrome P450 1A2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human CYP1A2 expressed in baculovirus-infected insect cells using Luciferin-1A2 as substrate in presence of NADPH by P450-Glo luminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cells using Luciferin-ME EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human CYP2C19 expressed in baculovirus-infected insect cells using Luciferin-H EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human ERG by Tracer Red dye based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cells using Luciferin-ME EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50: 2.74E+4nMAssay Description:Inhibition of human CYP3A4 expressed in baculovirus-infected insect cells using Luciferin-PFBE as substrate in presence of NADPH by P450-Glo luminesc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50: 4.21E+4nMAssay Description:Inhibition of human CYP2C9 expressed in baculovirus-infected insect cells using Luciferin-H as substrate in presence of NADPH by P450-Glo luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C9 expressed in baculovirus-infected insect cells using Luciferin-H as substrate in presence of NADPH by P450-Glo luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2 expressed in baculovirus-infected insect cells using Luciferin-1A2 as substrate in presence of NADPH by P450-Glo luminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by Tracer Red dye based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in baculovirus-infected insect cells using Luciferin-PFBE as substrate in presence of NADPH by P450-Glo luminesc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19 expressed in baculovirus-infected insect cells using Luciferin-H EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details Article
PubMed