Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50049319
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238966(CHEMBL4095230)
Affinity DataIC50: 420nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238965(CHEMBL4087528)
Affinity DataIC50: 450nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238962(CHEMBL4067813)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238967(CHEMBL4086544)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50341989(3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238964(CHEMBL4102979)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238963(CHEMBL4078699)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed