Compile Data Set for Download or QSAR
Report error Found 137 Enz. Inhib. hit(s) with all data for entry = 50048992
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232609(CHEMBL4098776)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232611(CHEMBL4071859)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232609(CHEMBL4098776)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232599(CHEMBL4095046)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206243(CHEMBL3918431)
Affinity DataEC50:  9.30nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232594(CHEMBL4102566)
Affinity DataEC50:  11nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50211215(CHEMBL3898922)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232610(CHEMBL4089244)
Affinity DataEC50:  18nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232613(CHEMBL4061082)
Affinity DataEC50:  18nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232600(CHEMBL4074583)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232611(CHEMBL4071859)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232598(CHEMBL4084852)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232595(CHEMBL4100355)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232612(CHEMBL4098850)
Affinity DataEC50:  29nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232606(CHEMBL4083246)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232605(CHEMBL4077222)
Affinity DataEC50:  33nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232616(CHEMBL4101249)
Affinity DataEC50:  34nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232601(CHEMBL4079623)
Affinity DataEC50:  43nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232599(CHEMBL4095046)
Affinity DataEC50:  78nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232607(CHEMBL4063152)
Affinity DataEC50:  84nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232602(CHEMBL4097654)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50211215(CHEMBL3898922)
Affinity DataEC50:  110nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232600(CHEMBL4074583)
Affinity DataEC50:  110nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232610(CHEMBL4089244)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232598(CHEMBL4084852)
Affinity DataEC50:  120nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232608(CHEMBL4071766)
Affinity DataEC50:  120nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232595(CHEMBL4100355)
Affinity DataEC50:  130nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232603(CHEMBL4075880)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232613(CHEMBL4061082)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232593(CHEMBL4087500)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232614(CHEMBL4102804)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232612(CHEMBL4098850)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232605(CHEMBL4077222)
Affinity DataIC50: 350nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232596(CHEMBL4064914)
Affinity DataIC50: 440nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232617(CHEMBL4066807)
Affinity DataEC50:  440nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232602(CHEMBL4097654)
Affinity DataEC50:  470nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206243(CHEMBL3918431)
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232603(CHEMBL4075880)
Affinity DataEC50:  480nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232614(CHEMBL4102804)
Affinity DataEC50:  630nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232593(CHEMBL4087500)
Affinity DataEC50:  630nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232596(CHEMBL4064914)
Affinity DataEC50:  840nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232606(CHEMBL4083246)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232607(CHEMBL4063152)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232604(CHEMBL4093500)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232615(CHEMBL4091037)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206243(CHEMBL3918431)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232594(CHEMBL4102566)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232616(CHEMBL4101249)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232594(CHEMBL4102566)
Affinity DataIC50: 9.20E+3nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232617(CHEMBL4066807)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
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