Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50048949
TargetPlatelet-derived growth factor receptor alpha(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PDGFRalpha (unknown origin) preincubated for 10 mins followed by FAM-labeled peptide substrate addition measured after 1 hr by mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human GST-tagged VEGFR3 cytoplasmic domain expressed in baculovirus expression system preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230972(CHEMBL4069394)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of PDGFRalpha (unknown origin) preincubated for 10 mins followed by FAM-labeled peptide substrate addition measured after 1 hr by mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230972(CHEMBL4069394)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of recombinant human GST-tagged VEGFR3 cytoplasmic domain expressed in baculovirus expression system preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230972(CHEMBL4069394)
Affinity DataIC50: 14nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human GST-tagged VEGFR1 cytoplasmic domain (781 to 1338 residues) expressed in baculovirus expression system preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230980(CHEMBL4091341)
Affinity DataIC50: 27nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230978(CHEMBL4086939)
Affinity DataIC50: 30nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230974(CHEMBL4070403)
Affinity DataIC50: 31nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230976(CHEMBL4079087)
Affinity DataIC50: 38nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230975(CHEMBL4059568)
Affinity DataIC50: 46nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230972(CHEMBL4069394)
Affinity DataIC50: 52nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230977(CHEMBL4061361)
Affinity DataIC50: 65nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230979(CHEMBL4098962)
Affinity DataIC50: 68nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230976(CHEMBL4079087)
Affinity DataIC50: 83nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230977(CHEMBL4061361)
Affinity DataIC50: 96nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230972(CHEMBL4069394)
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant human GST-tagged VEGFR1 cytoplasmic domain (781 to 1338 residues) expressed in baculovirus expression system preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant human GST-tagged FGFR1 cytoplasmic domain (398 to 822 residues) expressed in baculovirus expression system preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230975(CHEMBL4059568)
Affinity DataIC50: 138nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230980(CHEMBL4091341)
Affinity DataIC50: 153nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230974(CHEMBL4070403)
Affinity DataIC50: 165nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230979(CHEMBL4098962)
Affinity DataIC50: 165nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230978(CHEMBL4086939)
Affinity DataIC50: 168nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50230972(CHEMBL4069394)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human GST-tagged FGFR1 cytoplasmic domain (398 to 822 residues) expressed in baculovirus expression system preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2019
Entry Details Article
PubMed