Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50049170
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50235600(CHEMBL3542268)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50235601(CHEMBL4089347)
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50235598(CHEMBL4066845)
Affinity DataIC50: 24nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50235599(CHEMBL4088135)
Affinity DataIC50: 34nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed