Compile Data Set for Download or QSAR
Report error Found 124 Enz. Inhib. hit(s) with all data for entry = 50000384
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248627(CHEMBL4078454)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of full length recombinant human His-tagged CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248633(CHEMBL4083552)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248686(CHEMBL4071040)
Affinity DataEC50:  0.350nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248645(CHEMBL4061525)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248623(CHEMBL4096487)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length recombinant human His-tagged CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248656(CHEMBL4086487)
Affinity DataEC50:  0.400nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248614(CHEMBL4066819)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248635(CHEMBL4070408)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248633(CHEMBL4083552)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248656(CHEMBL4086487)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248656(CHEMBL4086487)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248645(CHEMBL4061525)
Affinity DataEC50:  0.580nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248645(CHEMBL4061525)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248640(CHEMBL4074204)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248690(CHEMBL4082469)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248633(CHEMBL4083552)
Affinity DataEC50:  0.770nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248635(CHEMBL4070408)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248611(CHEMBL4060856)
Affinity DataIC50: 0.930nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248611(CHEMBL4060856)
Affinity DataIC50: 0.970nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248638(CHEMBL4062244)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248614(CHEMBL4066819)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248612(CHEMBL4076395)
Affinity DataIC50: 1nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248640(CHEMBL4074204)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248615(CHEMBL4077627)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248686(CHEMBL4071040)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248614(CHEMBL4066819)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248638(CHEMBL4062244)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248690(CHEMBL4082469)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248611(CHEMBL4060856)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248686(CHEMBL4071040)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248662(CHEMBL4091345)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248615(CHEMBL4077627)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248615(CHEMBL4077627)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248612(CHEMBL4076395)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248635(CHEMBL4070408)
Affinity DataEC50:  2nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248640(CHEMBL4074204)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248632(CHEMBL4069854)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248687(CHEMBL4090775)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248687(CHEMBL4090775)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248612(CHEMBL4076395)
Affinity DataEC50:  2.60nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248662(CHEMBL4091345)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248632(CHEMBL4069854)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248638(CHEMBL4062244)
Affinity DataEC50:  3nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248662(CHEMBL4091345)
Affinity DataEC50:  3nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248690(CHEMBL4082469)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248609(CHEMBL4088931)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248658(CHEMBL4060714)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248639(CHEMBL4072372)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK8/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248658(CHEMBL4060714)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of kinase tracer-236 binding to GST-tagged CDK19/CyclinC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetCyclin-C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248628(CHEMBL4072496)
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant human His-tagged CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
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